D(+)-RIBONIC ACID GAMMA-LACTONE

Name	D-Ribono-1,4-lactone
Synonyms	NSC 1031 D-RIBOSE-LACTONE Ribono-gamma-lactone D-Ribono-1,4-lactone D-RIBONO-1,4-LACTONE D-Ribonolactone (VAN) D-Ribono-gamma-lactone D(+)-RIBONO-1,4-LACTONE D-Ribopentono-1,4-lactone D-(+)-RIBONO-GAMMA-LACTONE D-(+)-RIBONIC GAMMA-LACTONE D-(+)-RIBONIC ACID G-LACTONE D-Ribonic acid, 1,4-Lactone- gamma-Lactone of ribonic acid D-(+)-RIBONIC ACID GAMMA-LACTON D(+)-RIBONIC ACID GAMMA-LACTONE Ribonic acid, gamma-lactone, D- (3R,4S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-one 3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one (non-preferred name) (3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one (non-preferred name)
CAS	5336-08-3
EINECS	226-256-5
InChI	InChI=1/C5H8O5/c6-1-2-3(7)4(8)5(9)10-2/h2-4,6-8H,1H2/t2?,3-,4-/m1/s1

Molecular Formula	C5H8O5
Molar Mass	148.11
Density	1.2336 (rough estimate)
Melting Point	85-87°C(lit.)
Boling Point	188.68°C (rough estimate)
Specific Rotation(α)	18 º (c=5, H2O)
Flash Point	162.8°C
Water Solubility	soluble
Solubility	H2O: 0.1g/mL, clear
Vapor Presure	8.77E-07mmHg at 25°C
Appearance	Powder
Color	White to Pale Yellow
BRN	82057
pKa	12.10±0.60(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Stability	Stable
Refractive Index	18 ° (C=1, H2O)
MDL	MFCD00063241
Physical and Chemical Properties	White or yellowish crystals. Melting point 80 ℃ (85-87 ℃ ),[α] 18.4 °(C = 1,H2O), soluble in water, ethanol, acetone, slightly soluble in ethyl acetate, insoluble in ether.
Use	Important structural units for chiral acyclic, cyclopentenone and oxabicyclic systems. It is also used to study nonlinear optical materials.
In vitro study	Ki: 26 mM (β-galactosidase)

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29322090

NIST chemical information	Information provided by: webbook.nist.gov (external link)
Biological activity	D-Ribonolactone is a sugar lactone and an inhibitor of E. coli β-galactosidase (β-galactosidase), Ki is 26 mM.
use	vitamin B2 intermediate. It is a biochemical reagent, chiral acyclic or cyclic pentenone, and a synthetic reagent for oxabicyclic system.
production method	glucose can be oxidized, replaced, replaced and acidified to generate ribonic acid, and then heated to make internal esterification to obtain the product.

Last Update：2024-04-09 20:45:29

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D(+)-RIBONIC ACID GAMMA-LACTONE

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